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Cells depleted of mitochondrial DNA (p0) yield insight into physiological mechanisms
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Citing Literature
Number of times cited: 103
- Lihua Wang, Hong Lv, Pei Ji, Xun Zhu, Hua Yuan, Guangfu Jin, Juncheng Dai, Zhibin Hu, Yuxiong Su and Hongxia Ma, Mitochondrial DNA copy number is associated with risk of head and neck squamous cell carcinoma in Chinese population, Cancer Medicine, 7, 6, (2776-2782), (2018).
- A. Sen and R.T. Cox, Fly Models of Human Diseases, Fly Models of Human Diseases, 10.1016/bs.ctdb.2016.07.001, (1-27), (2017).
- Xiaoyu Long, Xiaoyan Wang, Yibing Chen, Xu Guo, Feng Zhou, Yongguo Fan, Naijian Ge, Mei Guo, Zhaohui Zhang and Guanglong Dong, Polymorphisms in POLG were associated with the prognosis and mtDNA content in hepatocellular carcinoma patients, Bulletin du Cancer, 10.1016/j.bulcan.2017.02.005, 104, 6, (500-507), (2017).
- Marike W. van Gisbergen, An M. Voets, Rianne Biemans, Roland F. Hoffmann, Marie-José Drittij-Reijnders, Guido R. M. M. Haenen, Irene H. Heijink, Kasper M. A. Rouschop, Ludwig J. Dubois, Philippe Lambin and Aamir Ahmad, Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress, PLOS ONE, 12, 8, (e0182508), (2017).
- Bo Wang, Jinsong Ao, Dan Yu, Ting Rao, Yuan Ruan and Xiaobin Yao, Inhibition of mitochondrial translation effectively sensitizes renal cell carcinoma to chemotherapy, Biochemical and Biophysical Research Communications, 490, 3, (767), (2017).
- Xuefeng Jia, Zhenfang Gu, Wenming Chen and Junbo Jiao, Tigecycline targets nonsmall cell lung cancer through inhibition of mitochondrial function, Fundamental & Clinical Pharmacology, 30, 4, (297-306), (2016).
- Hulin Chen, Junling Wang, Zhongrong Liu, Huilan Yang, Yingjie Zhu, Minling Zhao, Yan Liu and Miaomiao Yan, Mitochondrial DNA depletion causes decreased ROS production and resistance to apoptosis, International Journal of Molecular Medicine, 38, 4, (1039), (2016).
- Akinobu Akatsuka, Naoto Kojima, Mutsumi Okamura, Shingo Dan and Takao Yamori, A novel thiophene‐3‐carboxamide analog of annonaceous acetogenin exhibits antitumor activity via inhibition of mitochondrial complex I, Pharmacology Research & Perspectives, 4, 4, (2016).
- Kazunori Mori, Tetsu Uchida, Motonori Fukumura, Shigetoshi Tamiya, Masato Higurashi, Hirosato Sakai, Fumihiro Ishikawa and Motoko Shibanuma, Linkage of E2F1 transcriptional network and cell proliferation with respiratory chain activity in breast cancer cells, Cancer Science, 107, 7, (963), (2016).
- Ina Aretz, Christopher Hardt, Ilka Wittig and David Meierhofer, An Impaired Respiratory Electron Chain Triggers Down-regulation of the Energy Metabolism and De-ubiquitination of Solute Carrier Amino Acid Transporters, Molecular & Cellular Proteomics, 15, 5, (1526), (2016).
- Shasha Meng, Immaculata De Vivo, Liming Liang, Edward Giovannucci, Jean Y. Tang and Jiali Han, Pre-diagnostic leukocyte mitochondrial DNA copy number and skin cancer risk, Carcinogenesis, 37, 9, (897), (2016).
- Areum Jo, Sangwoo Ham, Gum Hwa Lee, Yun-Il Lee, SangSeong Kim, Yun-Song Lee, Joo-Ho Shin and Yunjong Lee, Efficient Mitochondrial Genome Editing by CRISPR/Cas9, BioMed Research International, 2015, (1), (2015).
- Meetha P. Gould, Colleen M. Bosworth, Sarah McMahon, Sneha Grandhi, Brian T. Grimerg, Thomas LaFramboise and Dan Mishmar, PCR-Free Enrichment of Mitochondrial DNA from Human Blood and Cell Lines for High Quality Next-Generation DNA Sequencing, PLOS ONE, 10, 10, (e0139253), (2015).
- J T Teh, W L Zhu, O R Ilkayeva, Y Li, J Gooding, P J Casey, S A Summers, C B Newgard and M Wang, Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism, Oncogene, 34, 25, (3296), (2015).
- Yu Jin Jeon, Hyoung Seok Kim, Kyung-Sik Song, Ho Jae Han, Soo Hyun Park, Woochul Chang and Min Young Lee, Protective effect of dieckol against chemical hypoxia-induced cytotoxicity in primary cultured mouse hepatocytes, Drug and Chemical Toxicology, 10.3109/01480545.2014.928719, 38, 2, (180-187), (2014).
- Yasuo Onishi, Takeshi Ueha, Teruya Kawamoto, Hitomi Hara, Mitsunori Toda, Risa Harada, Masaya Minoda, Masahiro Kurosaka and Toshihiro Akisue, Regulation of Mitochondrial Proliferation by PGC-1α Induces Cellular Apoptosis in Musculoskeletal Malignancies, Scientific Reports, 4, 1, (2015).
- Sebastien Michel, Morgane Canonne, Thierry Arnould and Patricia Renard, Inhibition of mitochondrial genome expression triggers the activation of CHOP-10 by a cell signaling dependent on the integrated stress response but not the mitochondrial unfolded protein response, Mitochondrion, 21, (58), (2015).
- Doaa I. Hashad, Amany S. Elyamany and Perihan E. Salem, Mitochondrial DNA Copy Number in Egyptian Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma, Genetic Testing and Molecular Biomarkers, 10.1089/gtmb.2015.0132, 19, 11, (604-609), (2015).
- Maja Grabacka, Malgorzata Gawin and Malgorzata Pierzchalska, Phytochemical Modulators of Mitochondria: The Search for Chemopreventive Agents and Supportive Therapeutics, Pharmaceuticals, 7, 12, (913), (2014).
- Ellen L. Robb and Jeffrey A. Stuart, The stilbenes resveratrol, pterostilbene and piceid affect growth and stress resistance in mammalian cells via a mechanism requiring estrogen receptor beta and the induction of Mn-superoxide dismutase, Phytochemistry, 10.1016/j.phytochem.2013.11.019, 98, (164-173), (2014).
- Weimin Zhou, Min Zhu, Ming Gui, Lihua Huang, Zhi Long, Li Wang, Hui Chen, Yinghao Yin, Xianzhen Jiang, Yingbo Dai, Yuxin Tang, Leye He, Kuangbiao Zhong and Craig N. Robson, Peripheral Blood Mitochondrial DNA Copy Number Is Associated with Prostate Cancer Risk and Tumor Burden, PLoS ONE, 9, 10, (e109470), (2014).
- Toshihiro Kushibiki, Takeshi Hirasawa, Shinpei Okawa and Miya Ishihara, Blue Laser Irradiation Generates Intracellular Reactive Oxygen Species in Various Types of Cells, Photomedicine and Laser Surgery, 31, 3, (95), (2013).
- Mario Negrette-Guzmán, Sara Huerta-Yepez, Edilia Tapia and José Pedraza-Chaverri, Modulation of mitochondrial functions by the indirect antioxidant sulforaphane: A seemingly contradictory dual role and an integrative hypothesis, Free Radical Biology and Medicine, 10.1016/j.freeradbiomed.2013.08.182, 65, (1078-1089), (2013).
- Ana P. Gomes, Nathan L. Price, Alvin J.Y. Ling, Javid J. Moslehi, Magdalene K. Montgomery, Luis Rajman, James P. White, João S. Teodoro, Christiane D. Wrann, Basil P. Hubbard, Evi M. Mercken, Carlos M. Palmeira, Rafael de Cabo, Anabela P. Rolo, Nigel Turner, Eric L. Bell and David A. Sinclair, Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging, Cell, 155, 7, (1624), (2013).
- E. Xu, W. Sun, J. Gu, W.-H. Chow, J. A. Ajani and X. Wu, Association of mitochondrial DNA copy number in peripheral blood leukocytes with risk of esophageal adenocarcinoma, Carcinogenesis, 34, 11, (2521), (2013).
- H. Xie, D. Lev, Y. Gong, S. Wang, R. E. Pollock, X. Wu and J. Gu, Reduced mitochondrial DNA copy number in peripheral blood leukocytes increases the risk of soft tissue sarcoma, Carcinogenesis, 10.1093/carcin/bgt023, 34, 5, (1039-1043), (2013).
- Hiroki Fujiwara, Shigeyuki Kawai and Kousaku Murata, Significance of sulfiredoxin/peroxiredoxin and mitochondrial respiratory chain in response to and protection from 100% O2 in Saccharomyces cerevisiae, Mitochondrion, 13, 1, (52), (2013).
- Gregory B. Waypa, Scott W. Osborne, Jeremy D. Marks, Sara K. Berkelhamer, Jyothisri Kondapalli and Paul T. Schumacker, Sirtuin 3 Deficiency Does Not Augment Hypoxia-Induced Pulmonary Hypertension, American Journal of Respiratory Cell and Molecular Biology, 49, 6, (885), (2013).
- Kaïs H. Al-Gubory, Mitochondria: Omega-3 in the route of mitochondrial reactive oxygen species, The International Journal of Biochemistry & Cell Biology, 44, 9, (1569), (2012).
- Yasuo Harada, Isao Ishii, Kiyohiko Hatake and Tadashi Kasahara, Pyrvinium pamoate inhibits proliferation of myeloma/erythroleukemia cells by suppressing mitochondrial respiratory complex I and STAT3, Cancer Letters, 319, 1, (83), (2012).
- J. T. Sylvester, Larissa A. Shimoda, Philip I. Aaronson and Jeremy P. T. Ward, Hypoxic Pulmonary Vasoconstriction, Physiological Reviews, 92, 1, (367), (2012).
- Yasuo Onishi, Teruya Kawamoto, Takeshi Ueha, Kenta Kishimoto, Hitomi Hara, Naomasa Fukase, Mitsunori Toda, Risa Harada, Masaya Minoda, Yoshitada Sakai, Masahiko Miwa, Masahiro Kurosaka, Toshihiro Akisue and Jorge Sans Burns, Transcutaneous Application of Carbon Dioxide (CO2) Induces Mitochondrial Apoptosis in Human Malignant Fibrous Histiocytoma In Vivo, PLoS ONE, 7, 11, (e49189), (2012).
- C C Cook, A Kim, S Terao, A Gotoh and M Higuchi, Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer, Cell Death & Disease, 3, 1, (e258), (2012).
- Ece A Mutlu, Phillip A Engen, Saul Soberanes, Daniela Urich, Christopher B Forsyth, Recep Nigdelioglu, Sergio E Chiarella, Kathryn A Radigan, Angel Gonzalez, Shriram Jakate, Ali Keshavarzian, GR Budinger and Gökhan M Mutlu, Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice, Particle and Fibre Toxicology, 8, 1, (19), (2011).
- Siyuan Zhao, Yefa Yang, Juan Liu, Hanqiang Liu, Naijian Ge, Hushan Yang, Hongxin Zhang and Jinliang Xing, Association of mitochondrial DNA content in peripheral blood leukocyte with hepatitis B virus‐related hepatocellular carcinoma in a Chinese Han population, Cancer Science, 102, 8, (1553-1558), (2011).
- Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim, Katherine A Fitzgerald, Stefan W Ryter and Augustine M K Choi, Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome, Nature Immunology, 12, 3, (222), (2011).
- Naomi Haga, Sakae Saito, Yoshinori Tsukumo, Junko Sakurai, Aki Furuno, Takashi Tsuruo and Akihiro Tomida, Mitochondria regulate the unfolded protein response leading to cancer cell survival under glucose deprivation conditions, Cancer Science, 101, 5, (1125), (2010).
- Zhimin Shi, Yixing Feng, Jianshe Wang, Hongxia Zhang, Lina Ding and Jiayin Dai, Perfluorododecanoic Acid-Induced Steroidogenic Inhibition is Associated with Steroidogenic Acute Regulatory Protein and Reactive Oxygen Species in cAMP-Stimulated Leydig Cells, Toxicological Sciences, 10.1093/toxsci/kfq014, 114, 2, (285-294), (2010).
- Marian L. Kruzel, Jeffrey K. Actor, Zsolt Radak, Attila Bacsi, Alfredo Saavedra-Molina and Istvan Boldogh, Lactoferrin decreases LPS-induced mitochondrial dysfunction in cultured cells and in animal endotoxemia model, Innate Immunity, 16, 2, (67), (2010).
- Dong Xiao, Anna A. Powolny, Michelle B. Moura, Eric E. Kelley, Ajay Bommareddy, Su-Hyeong Kim, Eun-Ryeong Hahm, Daniel Normolle, Bennett Van Houten and Shivendra V. Singh, Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells, Journal of Biological Chemistry, 10.1074/jbc.M109.063255, 285, 34, (26558-26569), (2010).
- Sruti Shiva, Mitochondria as metabolizers and targets of nitrite, Nitric Oxide, 22, 2, (64), (2010).
- Ashkan Emadi, Ashley E. Ross, Kathleen M. Cowan, Yolanda M. Fortenberry, Milena Vuica-Ross and Xuewen Pan, A Chemical Genetic Screen for Modulators of Asymmetrical 2,2′-Dimeric Naphthoquinones Cytotoxicity in Yeast, PLoS ONE, 5, 5, (e10846), (2010).
- Wei Qian and Bennett Van Houten, Alterations in bioenergetics due to changes in mitochondrial DNA copy number, Methods, 10.1016/j.ymeth.2010.03.006, 51, 4, (452-457), (2010).
- João Wosniak, Célio X. C. Santos, Alicia J. Kowaltowski and Francisco R. M. Laurindo, Cross-Talk Between Mitochondria and NADPH Oxidase: Effects of Mild Mitochondrial Dysfunction on Angiotensin II-Mediated Increase in Nox Isoform Expression and Activity in Vascular Smooth Muscle Cells, Antioxidants & Redox Signaling, 11, 6, (1265), (2009).
- Marco van der Toorn, Delaram Rezayat, Henk F. Kauffman, Stephan J. L. Bakker, Rijk O. B. Gans, Gerard H. Koëter, Augustine M. K. Choi, Antoon J. M. van Oosterhout and Dirk-Jan Slebos, Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells, American Journal of Physiology-Lung Cellular and Molecular Physiology, 297, 1, (L109), (2009).
- Brooke M. Emerling, Frank Weinberg, Colleen Snyder, Zach Burgess, Gökhan M. Mutlu, Benoit Viollet, G.R. Scott Budinger and Navdeep S. Chandel, Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio, Free Radical Biology and Medicine, 46, 10, (1386), (2009).
- Frank Weinberg and Navdeep S. Chandel, Reactive oxygen species-dependent signaling regulates cancer, Cellular and Molecular Life Sciences, 10.1007/s00018-009-0099-y, 66, 23, (3663-3673), (2009).
- Colleen M. Snyder and Navdeep S. Chandel, Mitochondrial Regulation of Cell Survival and Death During Low-Oxygen Conditions, Antioxidants & Redox Signaling, 11, 11, (2673), (2009).
- Dong Xiao, Anna A. Powolny, Jedrzej Antosiewicz, Eun-Ryeong Hahm, Ajay Bommareddy, Yan Zeng, Dhimant Desai, Shantu Amin, Anna Herman-Antosiewicz and Shivendra V. Singh, Cellular Responses to Cancer Chemopreventive Agent D,L-Sulforaphane in Human Prostate Cancer Cells Are Initiated by Mitochondrial Reactive Oxygen Species, Pharmaceutical Research, 10.1007/s11095-009-9883-5, 26, 7, (1729-1738), (2009).
- V.I. Grishko, R. Ho, G.L. Wilson and A.W. Pearsall, Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes, Osteoarthritis and Cartilage, 17, 1, (107), (2009).
- Lyudmila I. Rachek, Larysa V. Yuzefovych, Susan P. LeDoux, Neil L. Julie and Glenn L. Wilson, Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes, Toxicology and Applied Pharmacology, 240, 3, (348), (2009).
- Guofei Zhou, Laura A. Dada, Minghua Wu, Aileen Kelly, Humberto Trejo, Qiyuan Zhou, John Varga and Jacob I. Sznajder, Hypoxia-induced alveolar epithelial-mesenchymal transition requires mitochondrial ROS and hypoxia-inducible factor 1, American Journal of Physiology-Lung Cellular and Molecular Physiology, 297, 6, (L1120), (2009).
- Norbert Nass, Alexandra Kukat, Peter Seibel, Hans-Jürgen Brömme, Reinhard Schinzel, Rolf-Edgar Silber and Andreas Simm, Advanced glycation end product accumulation in rho0 cells without a functional respiratory chain, Biological Chemistry, 390, 9, (2009).
- Dong Xiao, Anna A. Powolny and Shivendra V. Singh, Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells, Journal of Biological Chemistry, 10.1074/jbc.M802529200, 283, 44, (30151-30163), (2008).
- N. Azad, A. K. V. Iyer, A. Manosroi, L. Wang and Y. Rojanasakul, Superoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosis, Carcinogenesis, 29, 8, (1538), (2008).
- Seweryn Mroczek and Joanna Kufel, Apoptotic signals induce specific degradation of ribosomal RNA in yeast, Nucleic Acids Research, 36, 9, (2874), (2008).
- Seigo Suzuki, Akihiro Naito, Takayuki Asano, Teresa T. Evans, Shrikanth A.G. Reddy and Masahiro Higuchi, Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a, Cancer Letters, 10.1016/j.canlet.2008.03.020, 268, 1, (31-37), (2008).
- T Klimova and N S Chandel, Mitochondrial complex III regulates hypoxic activation of HIF, Cell Death & Differentiation, 15, 4, (660), (2008).
- Guofei Zhou, Laura A. Dada and Jacob I. Sznajder, Chapter 7 Regulation of Na,K-ATPase by Reactive Oxygen Species, Free Radical Effects on Membranes, 10.1016/S1063-5823(08)00207-X, (131-146), (2008).
- J. Xing, M. Chen, C. G. Wood, J. Lin, M. R. Spitz, J. Ma, C. I. Amos, P. G. Shields, N. L. Benowitz, J. Gu, M. de Andrade, G. E. Swan and X. Wu, Mitochondrial DNA Content: Its Genetic Heritability and Association With Renal Cell Carcinoma, JNCI Journal of the National Cancer Institute, 100, 15, (1104), (2008).
- João Jr Wosniak, Celio X.C. Santos, Alícia Juliana Kowaltowski and Francisco Laurindo, Cross-talk between mitochondria and NADPH oxidase: Effects of mild mitochondrial dysfunction on angiotensin II mediated increase in Nox isoform expression and activity in vascular smooth muscle cells, Antioxidants & Redox Signaling, (110306091003087), (2008).
- Cheng-hui Xie, Akihiro Naito, Takatsugu Mizumachi, Teresa T. Evans, Michael G. Douglas, Craig A. Cooney, Chun-Yang Fan and Masahiro Higuchi, Mitochondrial regulation of cancer associated nuclear DNA methylation, Biochemical and Biophysical Research Communications, 364, 3, (656), (2007).
- Brian S. Zuckerbraun, Beek Yoke Chin, Martin Bilban, Joana de Costa d’Avila, Jayashree Rao, Timothy R. Billiar and Leo E. Otterbein, Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species, The FASEB Journal, 21, 4, (1099), (2007).
- Shigeru Sassa, Biological Implications of Heme Metabolism, Journal of Clinical Biochemistry and Nutrition, 38, 3, (138), (2006).
- Amanda L. Kalen, Ehab H. Sarsour, Sujatha Venkataraman and Prabhat C. Goswami, Mn-Superoxide Dismutase Overexpression Enhances G2Accumulation and Radioresistance in Human Oral Squamous Carcinoma Cells, Antioxidants & Redox Signaling, 8, 7-8, (1273), (2006).
- Robert D. Guzy and Paul T. Schumacker, Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia, Experimental Physiology, 91, 5, (807), (2006).
- Gregory B. Waypa and Paul T. Schumacker, Hypoxic pulmonary vasoconstriction: redox events in oxygen sensing, Journal of Applied Physiology, 98, 1, (404), (2005).
- Eugene G. Rikhvanov, Nina N. Varakina, Tatyana M. Rusaleva, Elena I. Rachenko, Dmitry A. Knorre and Victor K. Voinikov, Do mitochondria regulate the heat-shock response in Saccharomyces cerevisiae?, Current Genetics, 10.1007/s00294-005-0587-z, 48, 1, (44-59), (2005).
- Ludovic Mercy, Aurélia de Pauw, Laetitia Payen, Silvia Tejerina, Andrée Houbion, Catherine Demazy, Martine Raes, Patricia Renard and Thierry Arnould, Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+-dependent pathway and a reduced mitochondrial protein import, FEBS Journal, 272, 19, (5031), (2005).
- Kathryn A. Ziel, Valentina Grishko, Clayton C. Campbell, Jeffrey F. Breit, Glenn L. Wilson and Mark N. Gillespie, Oxidants in signal transduction: impact on DNA integrity and gene expression, The FASEB Journal, 19, 3, (387), (2005).
- Anthony A. Azenabor, Shoua Yang, Godwin Job and Olanrewaju O. Adedokun, Elicitation of reactive oxygen species in Chlamydia pneumoniae-stimulated macrophages: a Ca2+-dependent process involving simultaneous activation of NADPH oxidase and cytochrome oxidase genes, Medical Microbiology and Immunology, 194, 1-2, (91), (2005).
- Mir H. Ali, Daryl P. Pearlstein, Carol E. Mathieu and Paul T. Schumacker, Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransduction, American Journal of Physiology-Lung Cellular and Molecular Physiology, 287, 3, (L486), (2004).
- Patries M Herst, An S Tan, Debbie-Jane G Scarlett and Michael V Berridge, Cell surface oxygen consumption by mitochondrial gene knockout cells, Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1656, 2-3, (79), (2004).
- John J Haddad, Oxygen sensing and oxidant/redox-related pathways, Biochemical and Biophysical Research Communications, 316, 4, (969), (2004).
- Randall S. Frey and Asrar B. Malik, Oxidant signaling in lung cells, American Journal of Physiology-Lung Cellular and Molecular Physiology, 286, 1, (L1), (2004).
- Vijayalakshmi Panduri, Sigmund A. Weitzman, Navdeep S. Chandel and David W. Kamp, Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosis, American Journal of Physiology-Lung Cellular and Molecular Physiology, 286, 6, (L1220), (2004).
- Lodovica Vergani, Maura Floreani, Aaron Russell, Mara Ceccon, Eleonora Napoli, Anna Cabrelle, Lucia Valente, Federica Bragantini, Bertrand Leger and Federica Dabbeni-Sala, Antioxidant defences and homeostasis of reactive oxygen species in different human mitochondrial DNA-depleted cell lines, European Journal of Biochemistry, 271, 18, (3646), (2004).
- John J. Haddad, Hypoxia and the regulation of mitogen-activated protein kinases: gene transcription and the assessment of potential pharmacologic therapeutic interventions, International Immunopharmacology, 10.1016/j.intimp.2004.06.006, 4, 10-11, (1249-1285), (2004).
- Jiangang Shen, Nadeem Khan, Lionel D. Lewis, Ray Armand, Oleg Grinberg, Eugene Demidenko and Harold Swartz, Oxygen Consumption Rates and Oxygen Concentration in Molt-4 Cells and Their mtDNA Depleted (ρ0) Mutants, Biophysical Journal, 84, 2, (1291), (2003).
- Jacques Levraut, Hirotaro Iwase, Z.-H. Shao, Terry L. Vanden Hoek and Paul T. Schumacker, Cell death during ischemia: relationship to mitochondrial depolarization and ROS generation, American Journal of Physiology-Heart and Circulatory Physiology, 284, 2, (H549), (2003).
- M L Turcotte, M Parliament, A Franko and J Allalunis-Turner, Variation in mitochondrial function in hypoxia-sensitive and hypoxia-tolerant human glioma cells, British Journal of Cancer, 86, 4, (619), (2002).
- Vivian Y. Lee, David S. McClintock, Matthew T. Santore, G. R. Scott Budinger and Navdeep S. Chandel, Hypoxia Sensitizes Cells to Nitric Oxide-induced Apoptosis, Journal of Biological Chemistry, 277, 18, (16067), (2002).
- Dan He, Stavros Sougioultzis, Susan Hagen, Jennifer Liu, Sarah Keates, Andrew C. Keates, Charalabos Pothoulakis and J.Thomas LaMont, Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation, Gastroenterology, 122, 4, (1048), (2002).
- John J Haddad, Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology, Respiratory Research, 10.1186/rr190, 3, 1, (2002).
- Allison W. Dobson, Valentina Grishko, Susan P. LeDoux, Mark R. Kelley, Glenn L. Wilson and Mark N. Gillespie, Enhanced mtDNA repair capacity protects pulmonary artery endothelial cells from oxidant-mediated death, American Journal of Physiology-Lung Cellular and Molecular Physiology, 283, 1, (L205), (2002).
- G. R. Scott Budinger, May Tso, David S. McClintock, David A. Dean, Jacob I. Sznajder and Navdeep S. Chandel, Hyperoxia-induced Apoptosis Does Not Require Mitochondrial Reactive Oxygen Species and Is Regulated by Bcl-2 Proteins, Journal of Biological Chemistry, 277, 18, (15654), (2002).
- William C. Copeland, Joseph T. Wachsman, F. M. Johnson and John S. Penta, Mitochondrial DNA Alterations in Cancer, Cancer Investigation, 20, 4, (557), (2002).
- Karen Setterfield, Andrew J Williams, Jennifer Donald, David R Thorburn, Denise M Kirby, Ian Trounce and John Christodoulou, Flow cytometry in the study of mitochondrial respiratory chain disorders, Mitochondrion, 1, 5, (437), (2002).
- Paul T. Schumacker, Hypoxia, anoxia, and O2 sensing: the search continues, American Journal of Physiology-Lung Cellular and Molecular Physiology, 283, 5, (L918), (2002).
- Constancio Gonzalez, Gloria Sanz-Alfayate, M.Teresa Agapito, Angela Gomez-Niño, Asunción Rocher and Ana Obeso, Significance of ROS in oxygen sensing in cell systems with sensitivity to physiological hypoxia, Respiratory Physiology & Neurobiology, 10.1016/S1569-9048(02)00047-2, 132, 1, (17-41), (2002).
- Weiguo Zou, Mingda Yan, Weijing Xu, Hairong Huo, Lanying Sun, Zhongcheng Zheng and Xinyuan Liu, Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation, Journal of Neuroscience Research, 64, 6, (646), (2001).
- John S. Penta, F.M. Johnson, Joseph T. Wachsman and William C. Copeland, Mitochondrial DNA in human malignancy, Mutation Research/Reviews in Mutation Research, 488, 2, (119), (2001).
- Navdeep S. Chandel, Paul T. Schumacker and Robert H. Arch, Reactive Oxygen Species Are Downstream Products of TRAF-mediated Signal Transduction, Journal of Biological Chemistry, 276, 46, (42728), (2001).
- Yasuo Kagawa, Yutaka Inoki and Hitoshi Endo, Gene therapy by mitochondrial transfer, Advanced Drug Delivery Reviews, 49, 1-2, (107), (2001).
- Richard J. Rogers, Joan M. Monnier and Harry S. Nick, Tumor Necrosis Factor-α Selectively InducesMnSODExpression via Mitochondria-to-Nucleus Signaling, whereas Interleukin-1β Utilizes an Alternative Pathway, Journal of Biological Chemistry, 276, 23, (20419), (2001).
- Eugene Elmore, Thanh-Thuy Luc, Vernon E. Steele and J. Leslie Redpath, Comparative Tissue-Specific Toxicities of 20 Cancer Preventive Agents Using Cultured Cells From 8 Different Normal Human Epithelia, In Vitro & Molecular Toxicology, 14, 3, (191), (2001).
- L. Xue, G.C. Fletcher and A.M. Tolkovsky, Mitochondria are selectively eliminated from eukaryotic cells after blockade of caspases during apoptosis, Current Biology, 10.1016/S0960-9822(01)00100-2, 11, 5, (361-365), (2001).
- Valentina Grishko, Marie Solomon, Glenn L. Wilson, Susan P. LeDoux and Mark N. Gillespie, Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes, American Journal of Physiology-Lung Cellular and Molecular Physiology, 280, 6, (L1300), (2001).
- Navdeep S. Chandel and Paul T. Schumacker, Cellular oxygen sensing by mitochondria: old questions, new insight, Journal of Applied Physiology, 88, 5, (1880), (2000).
- Victor J. Thannickal and Barry L. Fanburg, Reactive oxygen species in cell signaling, American Journal of Physiology-Lung Cellular and Molecular Physiology, 279, 6, (L1005), (2000).
- Yasuo Kagawa, Seung Hun Cha, Kyoko Hasegawa, Toshiro Hamamoto and Hitoshi Endo, Regulation of Energy Metabolism in Human Cells in Aging and Diabetes: FoF1, mtDNA, UCP, and ROS, Biochemical and Biophysical Research Communications, 266, 3, (662), (1999).
- Ed Reznik, Martin L Miller, Yasin Şenbabaoğlu, Nadeem Riaz, Judy Sarungbam, Satish K Tickoo, Hikmat A Al-Ahmadie, William Lee, Venkatraman E Seshan, A Ari Hakimi and Chris Sander, Mitochondrial DNA copy number variation across human cancers, eLife, 10.7554/eLife.10769, 5, (2016).
- Rossana Mineri, Norman Pavelka, Erika Fernandez-Vizarra, Paola Ricciardi-Castagnoli, Massimo Zeviani, Valeria Tiranti and Thomas Preiss, How Do Human Cells React to the Absence of Mitochondrial DNA?, PLoS ONE, 10.1371/journal.pone.0005713, 4, 5, (e5713), (2009).




