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Volume 202, Issue 1 p. 101-106
Free Access

Isolation and characterization of a new variant of surfactin, the [Val7]surfactin

Françoise PEYPOUX

Corresponding Author

Françoise PEYPOUX

Laboratoire de Biochimie Microbienne, Université Claude Bernard Lyon I, Villeurbanne, France

Correspondence to F. Peypoux, Laboratoire de Biochimie Microbienne, Université Claude Bernard Lyon I, 43 Boulevard du 11 Novembre 1918, F-69622 Villeurbanne Cedex, FranceSearch for more papers by this author
Jean-Marc BONMATIN

Jean-Marc BONMATIN

Centre de Biophysique Moléculaire, Centre National de la Recherche Scientifique, Orléans et Université d'Orléans, France

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Henri LABBÉ

Henri LABBÉ

Centre de Biophysique Moléculaire, Centre National de la Recherche Scientifique, Orléans et Université d'Orléans, France

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Bhupesh C. DAS

Bhupesh C. DAS

Institut de Chimie des Substances Naturelles, Gif-sur-Yvette, France

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Marius PTAK

Marius PTAK

Centre de Biophysique Moléculaire, Centre National de la Recherche Scientifique, Orléans et Université d'Orléans, France

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Georges MICHEL

Georges MICHEL

Laboratoire de Biochimie Microbienne, Université Claude Bernard Lyon I, Villeurbanne, France

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First published: November 1991
Citations: 81

Abstract

Reinvestigation of surfactin, a previously studied peptidolipid surfactant from Bacillus subtilis, by fast-atom-bombardment mass spectrometry and 1H-NMR spectroscopy, as well as by chemical methods, revealed the presence of a closely related second constituent. This new compound, [Val7]surfactin, differs from the known surfactin by the C-terminal amino acid residue which is valine instead of leucine.

Abbreviations

  • FAB
  • fast atom bombardment
  • HOHAHA
  • homonuclear Hartman-Hahn
  • DQF-COSY
  • double-quantum-filter correlation spectroscopy
  • 1D
  • one-dimensional
  • 2D
  • two-dimensional