The FEBS Journal Richard Perham Prize

FEBS, and the Editorial Boards of its journals, is keen to support young scientists. To complement the many activities of FEBS in this area, The FEBS Journal awards an annual prize of €1000.

The FEBS Journal Richard Perham Prize is awarded to the first author of the best paper by a graduate student or young post doc (no more than 3 years from the date of award of the PhD degree when the paper is submitted) published in the journal during the previous calendar year.

Authors are asked to indicate their eligibility for the prize when submitting their manuscript. We regret that first authors of reviews and minireviews cannot be considered as candidates for the prize.

The choice of prize-winner will be made by the Editorial Board of the journal, whose decision will be final. The first author of the prize-winning paper, chosen from the papers published in 2016, will be invited to present his/her work in a plenary lecture at the annual FEBS Congress in 2017, where the prize will be awarded.

The prize is named in recognition of Richard Perham’s outstanding contributions to the journal and to FEBS.

Sebastian Bittner

The FEBS Journal Prizewinner 2017

The prize was awarded to Sebastian Bittner (University Hospital of Regensburg, Germany) for his outstanding paper:

Soluble TL1A is sufficient for activation of death receptor 3
Sebastian Bittner, Gertrud Knoll, Simone Füllsack, Maria Kurz, Harald Wajant and Martin Ehrenschwender

Death receptor 3 (DR3) and its ligand, TL1A, are members of the tumour necrosis factor receptor superfamily (TNFRSF) and TNF ligand superfamily (TNFSF), respectively. TL1A–DR3 signalling has a key role in the development of autoimmune and inflammatory diseases. Intriguingly, DR3-mediated signalling also increases the number of regulatory T cells to counteract inflammatory processes. Despite the prominence of TL1A–DR3 signalling in inflammation, the mechanism by which TL1A activates DR3 remained enigmatic. In the prize-winning work, Bittner and colleagues demonstrated that the soluble, trimeric form of TL1A is sufficient to trigger DR3 activation and subsequent internalisation. Further oligomerisation of TL1A does not enhance its signalling activity. Given the importance of the TL1A–DR3 interaction in autoimmune and inflammatory diseases, these findings provide an essential foundation for future therapeutic exploitation of this pathway.

Sebastian Bittner will present a plenary lecture about the prizewinning work at the FEBS Congress in Jerusalem, Israel in September 2017, where he will be officially presented with the prize.


The FEBS Journal Prizewinner 2016

The prize was awarded to Fatima Aloraifi (Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland) for her outstanding paper:

Detection of novel germline mutations for breast cancer in non-BRCA1/2 families
Fatima Aloraifi, Trudi McDevitt, Rui Martiniano, Jonah McGreevy, Russell McLaughlin, Chris M. Egan, Nuala Cody, Marie Meany, Elaine Kenny, Andrew J. Green, Daniel G. Bradley, James G. Geraghty and Adrian P. Bracken


The FEBS Journal Prizewinner 2014

Joint first authors Naima Zemirli and Marie Pourcelot of INSERM, UMR.1197, Hopital Paul Brousse and Universite Paris-Sud P11, Orsay, France for their outstanding paper:

Mitochondrial hyperfusion promotes NF-κB activation via the mitochondrial E3 ligase MULAN
Zemirli, N., Pourcelot, M., Ambroise, G., Hatchi, E., Vazquez, A. and Arnoult, D.

Listen to the podcast (MP3 file, 4.59MB, 4:54 minutes)

The FEBS Journal Prizewinner 2013

Hee-Yeon JeonHee-Yeon Jeon of the Department of Biological Sciences, Seoul National University, Korea, for her outstanding paper:

Depletion of Aurora-A in zebrafish causes growth retardation due to mitotic delay and p53-dependent cell death
Jeon, H.-Y. and Lee, H.

The FEBS Journal Prizewinner 2012

Anna-Karin GustavssonAnna-Karin Gustavsson of the Department of Physics, University of Gothenburg, for her outstanding paper:

Sustained glycolytic oscillations in individual isolated yeast cells
Gustavsson, A.-K., van Niekerk, D. D., Adiels, C. B., du Preez, F. B., Goksör, M. and Snoep, J. L.

Listen to the podcast (MP3 file, 4.52MB, 4:56 minutes)

The FEBS Journal Prizewinner 2011

Rosemarie Carew Rosemarie Carew of the UCD Diabetes Research Centre, UCD Conway Institute, University College Dublin, Ireland, for her outstanding paper:

Insulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression and transforming growth factor-b1-induced repression in kidney epithelial cells
Rosemarie M. Carew, Marie B. Browne, Fionnuala B. Hickey and Derek P. Brazil

Listen to the podcast (MP3 file, 4.47 MB, 4:53 minutes)

Karen van EunenThe FEBS Journal Prizewinner 2010

Karen van Eunen of the Department of Pediatrics, Center for Liver, Digestive and Metabolic Disease, University Medical Center Groningen, Groningen, The Netherlands for her outstanding paper:

Measuring enzyme activities under standardized in vivo-like conditions for systems biology
Karen van Eunen, Jildau Bouwman, Pascale Daran-Lapujade, Jarne Postmus, André B. Canelas, Femke I. C. Mensonides, Rick Orij, Isil Tuzun, Joost van den Brink, Gertien J. Smits, Walter M. van Gulik, Stanley Brul, Joseph J. Heijnen, Johannes H. de Winde, M. Joost Teixeira de Mattos, Carsten Kettner, Jens Nielsen, Hans V. Westerhoff & Barbara M. Bakker

Mercedes Nancy Munkonda The FEBS Journal Prizewinner 2009

Mercedes Nancy Munkonda of the Rheumatology and Immunology Research Center, Laval University, Québec, Canada (currently at: the Institute of Cardiology and Pneumology, Laval University, Québec, Canada), for her outstanding paper:

Characterization of a monoclonal antibody as the first specific inhibitor of human NTP diphosphohydrolase-3: Partial characterization of the inhibitory epitope and potential applications
Mercedes N. Munkonda, Julie Pelletier, Vasily V. Ivanenkov, Michel Fausther, Alain Tremblay, Beat Künzli, Terence L. Kirley and Jean Sévigny

Simon GunningThe FEBS Journal Prizewinner 2008

Simon Gunning of the Department of Medical & Molecular Biosciences, University of Technology, Sydney, Australia, for his outstanding paper:

The Janus-faced atracotoxins are specific blockers of invertebrate KCa channels
Simon J. Gunning, Francesco Maggio, Monique J. Windley, Stella M. Valenzuela, Glenn F. King and Graham M. Nicholson

Xueyan ZhaoThe FEBS Journal Prizewinner 2007

Xueyan Zhao of the Department of Cell Biology, University of Alabama at Birmingham, USA, for her outstanding paper:

The interferon-stimulated gene factor 3 complex mediates the inhibitory effect of interferon-β on matrix metalloproteinase-9 expression
Xueyan Zhao, Susan Nozell, Zhendong Ma and Etty N. Benveniste

Hakan DortayThe FEBS Journal Prizewinner 2006

Hakan Dortay of the Institute of Biology/Applied Genetics, Free University of Berlin, Germany (currently at: Department of Biochemistry and Biology, Institute of Molecular Biology and Plant Physiology, University of Potsdam, Germany), for his outstanding paper:

Analysis of protein interactions within the cytokinin-signaling pathway of Arabidopsis thaliana
Hakan Dortay, Nijuscha Mehnert, Lukas Bürkle, Thomas Schmülling and Alexander Heyl

Nicole LaRonde-LeBlancThe FEBS Journal Prizewinner 2005

Nicole LaRonde-LeBlanc of the Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, MD, for her outstanding paper:

Structure and activity of the atypical serine kinase Rio1
Nicole LaRonde-LeBlanc, Tad Guszczynski, Terry Copeland and Alexander Wlodawer

Christian KlammtThe FEBS Journal Prizewinner 2004

Christian Klammt of the Center for Biomolecular Magnetic Resonance, University of Frankfurt/Main Institute for Biophysical Chemistry, for his outstanding paper:

High level cell-free expression and specific labeling of integral membrane proteins
Christian Klammt, Frank Löhr, Birgit Schäfer, Winfried Haase, Volker Dötsch, Heinz Rüterjans, Clemens Glaubitz and Frank Bernhard