FEBS Press is pleased to welcome its fourth journal, Molecular Oncology, to this platform. Molecular Oncology is now fully Open Access and all content from the past 10 years is now available for all to read. The publication of high-quality journals by scientists for scientists is one the core objectives of The Federation of European Biochemical Societies (FEBS), with the revenue raised supporting fellowships, courses, congresses and other activities.

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The FEBS Journal For high-quality full-length papers and reviews, with particular focus on biochemistry, molecular biology, structural biology and cell biology.
FEBS Letters For highly significant research letters that merit urgent publication, as well as timely reviews of wide interest in the molecular biosciences.
Molecular OncologyFor high-impact discoveries, approaches and technical advances in basic, clinical and discovery-driven translational cancer research.
FEBS Open Bio For rapid open access publication of scientifically sound research articles in the molecular and cellular life sciences.

Highlighted Articles

Minireview Series on Matrix Pathobiology

New Minireview Series on Matrix Pathobiology from The FEBS Journal

This Minireview Series from The FEBS Journal presents three timely reviews covering the latest research on key extracellular matrix molecules and their roles in cancer. Iozzo and colleagues review the roles of biglycan and decorin during inflammation and autophagy in cancer [1]. Karamanos and colleagues highlight the emergence of syndecans as prognostic tools for cancer progression [2]. Sanderson and colleagues discuss regulatory roles of heparanase in inflammation, autophagy and cancer progression [3].

Shibata and colleagues

The calcium-binding protein ALG-2 promotes endoplasmic reticulum exit site localization and polymerization of Trk-fused gene (TFG) protein

Shibata and colleagues, The FEBS Journal

Apoptosis-linked gene 2 (ALG-2) mediates calcium-dependent signalling by interacting with effector proteins. Shibata and colleagues now show that ALG-2 also functions as an adaptor protein that promotes the polymerisation of Trk-fused gene (TFG) and its recruitment to endoplasmic reticulum exit sites (ERES) in a calcium-dependent manner. This study supports a role for ALG-2 as an adaptor protein involved in COPII-mediated protein trafficking from the ER.

Sekito, T. and colleagues

Functional identification of AtAVT3, a family of vacuolar amino acid transporters, in Arabidopsis

Sekito, T. and colleagues, FEBS Letters

In plants, amino acids are stored in the vacuoles of young leaves, and actively exported to the cytosol under low nitrogen supply. The molecular identity of these transporters was unknown so far. Here, using a heterologous expression system in yeast, the authors identify the AtAVT3-related genes as a family of amino acid transporters that play a role in the export of neutral amino acids across the vacuolar membrane in plants.

von Heijne, G. and colleagues

Mutational analysis of protein folding inside the ribosome exit tunnel

von Heijne, G. and colleagues, FEBS Letters

Ribosome stalling during translation of arrest peptide (AP) sequences may be overcome by pulling forces exerted on nascent polypeptide chains during cotranslational protein folding. Here, Farías-Rico et al. combine AP-based force sensors with Ala and Trp scanning to provide insights into cotranslational folding of the ADR1a zinc-finger domain within the ribosome exit tunnel. The method utilized expands the toolkit available for investigating intraribosomal protein folding.

Arkov and colleagues

In vivo mapping of a dynamic ribonucleoprotein granule interactome in early Drosophila embryos

Arkov and colleagues, FEBS Open Bio

Large macromolecular complexes are crucial to cellular life, but details of their intricate architecture are often poorly understood. In this study, Arkov and colleagues employed a new in vivo crosslinking approach to map and position granular components in the evolutionarily conserved germ granule. Using a Drosophila embryo, the authors investigated the molecular neighbourhood of the germ granule, providing evidence that it contains efficient biochemical reactors involved in post-transcriptional gene regulation.

FEBS Press News

This special issue focusses on the molecular mechanisms driving cancer metastasis

FEBS Open Bio is celebrating its 5th anniversary - take a look at their new Virtual Issues showcasing content in Cancer biology, Microbiology, Plant Biology, and Computational and Systems Biology

NobelRead the celebratory FEBS Letters Virtual Issue "Autophagy: The 2016 Nobel Prize" collecting studies by Yoshinori Ohsumi and his coworkers

This Virtual Issue showcases specially selected articles from the FEBS Press journals - The FEBS Journal, FEBS Letters and FEBS Open Bio - published in 2016

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    News from FEBS

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    Ottoline Leyser honouredOttoline Leyser honoured with the 2017 FEBS | EMBO Women in Science Award
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    Abstract submission to FEBS 2017 is now openAbstract submission to FEBS 2017 is now open
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    FEBS Letters November Issue 2016Five years on: FEBS Open Bio celebrates its launch anniversary
    Happy Birthday to our newest journal...